This post is not just geared to anyone with kidney disease, but to anyone who is concerned about their overall health and well being. What I am talking about concerns the overuse of proton pump inhibitors. Don't get me wrong. They do have a place for short term use if you have a really bad ulcer or significant gastric inflammation. It is the long term overuse that I believe to be a problem.
Your stomach needs to be acidic to digest the food that you eat. God made us this way. Without an acidic pH in the stomach (ie the gastric area), food does not get digested, nutrients do not get absorbed. Vitamin D absorption, B12 absorption, and other nutrients are affected.
Here are a couple of links to articles where the long term use of these medications may increase the risk of osteoporosis (this point is controversial in some studies), B12 deficiency, as well as the increase of one of the most dreaded hospital infections, Clostridium difficile colitis.
Here are a couple of links talking about the dangers of overuse of these medications:
http://www.ncbi.nlm.nih.gov/pubmed/22095013
http://www.ncbi.nlm.nih.gov/pubmed/21909830
http://www.ncbi.nlm.nih.gov/pubmed/20582909
What does this teach us? The key is to keep ourselved in balance. When the body is out of balance, bad things can happen. Overuse of PPIs puts the body totally out of balance.
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