Tuesday, September 27, 2011

Cam there be too much Vitamin D?

One thing that came out of my talk with Dr Mayer is the question: are we taking too much Vitamin D? The study we talked about during the show discussed that those males with Vit D levels in the 60-70 range had an increased risk of obtaining prostate cancer. The article concluded that too much Vitamin D in men may increase the risk of cancer and cautioned men not to ingest too much Vitamin D.

In the past year we have heard about the epidemic of Votamin D deficiency and of its importance  in the body. I am in no way denying any of this. Here is this question though: what is the optimal dose? Optimal means not too much and not too little. Maybe the calcidiol level is not the most optimal way to measure vitamin D.

Consider another thought process, one that a colleagure shared with me. Vitamin D3 is an oil; it is a fat soluble vitamin. If the gut is not intact, ie,"leaky-gut syndrome", then not all of the vitamin D will be absorbed. What happens to the excess vitamin D that is not absorbed? Could it circulate in the bloodstream, become oxidized, and contribute to atherogenesis?

I had not thought about this aspect before. This then brings uo another question. Is one of the contributing factors to vitamin D deficiency the fact that our intestinal tract is not intact? Dysbiosis, altered bwel flora, may lead to low vitamin d levels. I would love to see a study where vitamin d levels were measured  in the blood, dose unchanged: in one group a probiotic would not be given, in the other, one would be. It would be interesting to see if there would be any differences.

I think the study discussed during this show tells us one thing: too much of anything is not good.

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